Papers of interest

Below Pelican has listed a selection of papers that reflect the areas of research that we have been involved in and continue to support. Where possible the links to the abstracts are included for further information.

“Focal Salvage Therapy for Localized Prostate Cancer Recurrence After External Beam Radiotherapy: A Pilot Study.”Ahmed, Hashim Uddin, Paul Cathcart, Neil McCartan, Alex Kirkham, Clare Allen, Alex Freeman, and Mark Emberton Cancer 118, no. 17 (September 1, 2012): 4148-4155. doi:10.1002/cncr.27394.

“Whole-gland Salvage High-intensity Focused Ultrasound Therapy for Localized Prostate Cancer Recurrence After External Beam Radiation Therapy.” Uddin Ahmed, Hashim, Paul Cathcart, Venu Chalasani, Andrew Williams, Neil McCartan, Alex Freeman, Alex Kirkham, Clare Allen, Joseph Chin, and Mark Emberton.Cancer 118, no. 12 (June 15, 2012): 3071-3078. doi:10.1002/cncr.26631.

“Image-directed, Tissue-preserving Focal Therapy of Prostate Cancer: a Feasibility Study of a Novel Deformable Magnetic Resonance-ultrasound (MR-US) Registration System: A Novel Deformable MR-US Registration System.”Dickinson, Louise et al. BJU International 112.5 (2013): 594–601. CrossRef. Web. 24 Sept. 2013.

“Image-Directed, Tissue-Preserving Focal Therapy of Prostate Cancer: A Feasibility Study of a Novel Deformable Mr-Us Registration System.”Dickinson, L et al. BJU International (2013): Wiley Online Library. Web. 15 May 2013.

“Focal HIFU for Prostate Cancer.” Challacombe, Ben, Prokar Dasgupta, Roger Kirby, John Fitzpatrick, and William Catalona. The Lancet Oncology 13, no. 7 (July 2012): e283-284; author reply e284. doi:10.1016/S1470-2045(12)70306-6.

“Focal Therapy for Localised Unifocal and Multifocal Prostate Cancer: a Prospective Development Study.” Ahmed, Hashim U, Richard G Hindley, Louise Dickinson, Alex Freeman, Alex P Kirkham, Mahua Sahu, Rebecca Scott, Clare Allen, Jan Van der Meulen, and Mark Emberton.The Lancet Oncology 13, no. 6 (June 2012): 622-632. doi:10.1016/S1470-2045(12)70121-3.

“Transatlantic Consensus Group on Active Surveillance and Focal Therapy for Prostate Cancer.”Ahmed, Hashim U, Oguz Akin, Jonathan A Coleman, Sarah Crane, Mark Emberton, Larry Goldenberg, Hedvig Hricak, et al. BJU International 109, no. 11 (June 2012): 1636-1647. doi:10.1111/j.1464-410X.2011.10633.x.

“Clinical Applications of Multiparametric MRI Within the Prostate Cancer Diagnostic Pathway.” Dickinson, Louise, Hashim U. Ahmed, Clare Allen, Jelle O. Barentsz, Brendan Carey, Jurgen J. Futterer, Stijn W. Heijmink, et al. Urologic Oncology: Seminars and Original Investigations (March 2012). doi:10.1016/j.urolonc.2012.02.004.

“Roundtable Discussion – Focal Therapy for Prostate Cancer.” Bomers, Joyce, Louise Dickinson, Jurgen J. Fütterer, Jelle Barentsz, Aaron Katz, Laurence Klotz, Mark Schoenberg, and Osamu Ukimura. European Urological Review 7, no. 2 (2012): 101-5.

“Focal Therapy for Localized Prostate Cancer: A Phase I/II Trial.” Ahmed, H.U., A. Freeman, A. Kirkham, M. Sahu, R. Scott, C. Allen, J. Van der Meulen, and M. Emberton. The Journal of Urology 185, no. 4 (April 2011): 1246-1255. doi:10.1016/j.juro.2010.11.079.

“ESUR Prostate MR Guidelines 2012.” Barentsz, Jelle O, Jonathan Richenberg, Richard Clements, Peter Choyke, Sadhna Verma, Geert Villeirs, Olivier Rouviere, Vibeke Logager, and Jurgen J Fütterer. European Radiology 22, no. 4 (April 2012): 746-757. doi:10.1007/s00330-011-2377-y.

“Magnetic Resonance Imaging for the Detection, Localisation, and Characterisation of Prostate Cancer: Recommendations from a European Consensus Meeting.” Dickinson, Louise, Hashim U Ahmed, Clare Allen, Jelle O Barentsz, Brendan Carey, Jurgen J Futterer, Stijn W Heijmink, et al.European Urology 59, no. 4 (April 2011): 477-494. doi:10.1016/j.eururo.2010.12.009.

“MR Imaging of Prostate After Treatment with High-intensity Focused Ultrasound.” Kirkham, Alexander P S, Mark Emberton, Ivan M Hoh, Rowland O Illing, A Alex Freeman, and Clare Allen. Radiology246, no. 3 (March 2008): 833-844. doi:10.1148/radiol.2463062080.

Can we deliver randomized trials of focal therapy in prostate cancer? Ahmed HU, Berge V, Bottomley D, Cross W, Heer R, Kaplan R, Leslie T, Parker C, Relton C, Stephens R, Sydes MR, Turnbull L, van der Meulen J, Vickers A, Wilt T, Emberton M; the Prostate Cancer RCT Consensus Group. Nat Rev Clin Oncol. 2014 Apr 22. doi: 10.1038/nrclinonc.2014.44. [Epub ahead of print]

Management of low risk prostate cancer: active surveillance and focal therapy. Klotz L, Emberton M. Nat Rev Clin Oncol. 2014 Jun;11(6):324-34

Can MRI replace serial biopsies in men on active surveillance for prostate cancer? Moore CM, Petrides N, Emberton M. Curr Opin Urol. 2014 May: 24(3):280-7

Multiparametric magnetic resonance imaging in the management and diagnosis of prostate cancer: current applications and strategies. Lee DJ, Ahmed HU, Moore CM, Emberton M, Ehdaie B. Curr Urol Rep. 2014 Mar; 15(3): 390

Morbidity Associated with Primary High Intensity Focused Ultrasound and Redo High Intensity Focused Ultrasound for Localized Prostate Cancer. Berge V, Dickinson L, McCartan N, Hindley RG, Diep LM, Emberton M, Ahmed HU. J Urol. 2013 Dec 25 . pii: S0022-5347(13)06138-7. doi: 10.1016/j.juro.2013.12.036. [Epub ahead of print]

Prostate Cancer Tumour Features on Template Prostate-mapping Biopsies: Implications for Focal Therapy. Singh PB, Anele C, Dalton E, Barbouti O, Stevens D, Gurung P, Arya M, Jameson C, Freeman A, Emberton M, Ahmed HU. Eur Urol. 2014 Jul; 66(1): 12-9

Are we ready for the new wave of focal therapy interventions for men with early prostate cancer? Emberton M. BJU Int. 2013 Aug; 112(4):423-4

The Role of Focal Therapy in the Management of Localised Prostate Cancer: A Systematic Review. Valerico M, Ahmed HU, Emberton M, Lawrentschuk N, Lazzeri M, Montironi R, Nguyen PL, Trachtenberg J, Polascik TJ. Eur Urol. 2013 Jun 6 pii: S0302-2838(13)00557-5. doi: 10.1016/j.eururo.2013.05.048. [Epub ahead of print]